Controlling cell migration

Latest research

1. 1. Developmental Biology
   2. Neuroscience

   Energetic Demands Regulate Sleep-Wake Rhythm Circuit Development

   Amy R. Poe, Lucy Zhu ... Matthew S. Kayser
2. 1. Neuroscience

   A septo-hypothalamic-medullary circuit directs stress-induced analgesia

   Devanshi Piyush Shah, Pallavi Raj Sharma ... Arnab Barik
3. 1. Neuroscience

   Using normative models pre-trained on cross-sectional data to evaluate longitudinal changes in neuroimaging data

   Barbora Rehák Bučková, Charlotte Fraza ... Jaroslav Hlinka
4. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Transposon mutagenesis screen in Klebsiella pneumoniae identifies genetic determinants required for growth in human urine and serum

   Jessica Gray, Von Vergel L Torres ... Ian R Henderson
5. 1. Immunology and Inflammation

   Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity

   Leen Farhat-Younis, Manho Na ... Yaron Carmi
6. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

   Gregory Caleb Howard, Jing Wang ... William P Tansey

   Analysis of the action of WDR5 inhibitors in leukemia cells reveals decreased ribosome inventory, impaired protein synthesis, induction of nucleolar stress, and activation of p53 via alternative splicing of MDM4.
7. 1. Neuroscience

   A new ‘CFS tracking’ paradigm reveals uniform suppression depth regardless of target complexity or salience

   David Alais, Jacob Coorey ... Matthew J Davidson

   A new and efficient continuous flash suppression (CFS) method is presented that provides breakthrough and suppression thresholds to quantify depth of target suppression.
8. 1. Computational and Systems Biology
   2. Physics of Living Systems

   Development of equation of motion deciphering locomotion including omega turns of Caenorhabditis elegans

   Taegon Chung, Iksoo Chang, Sangyeol Kim

   ElegansBot, a two-dimensional rigid body chain model, simulates various locomotion of C. elegans, including omega and delta turns, using Newtonian equations of motion.
9. 1. Cancer Biology
   2. Cell Biology

   N-cadherin directs the collective Schwann cell migration required for nerve regeneration through Slit2/3-mediated contact inhibition of locomotion

   Julian JA Hoving, Elizabeth Harford-Wright ... Alison C Lloyd

   N-cadherin and Slit2/3/Robo interactions provide the outward force to drive collective Schwann cell migration during nerve regeneration, identifying a dual role for N-cadherin in both adhesion and repulsion processes during Schwann cell collective migration.
10. 1. Microbiology and Infectious Disease

    Birnaviral Hijacking of Endosomal Membranes

    Flavia A. Zanetti, Ignacio Fernández ... Laura R. Delgui